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Reconstruction of images at intermediate phases of lung 4D-CT data based on deformable registration
GENG Dandan, WANG Tingting, CAO Lei, ZHANG Yu
Journal of Computer Applications    2015, 35 (4): 1120-1123.   DOI: 10.11772/j.issn.1001-9081.2015.04.1120
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Due to the high radiation dose to the patient when acquiring lung four Dimensional Computed Tomography (4D-CT) data, this paper proposed a method for deriving the phase-binned 4D-CT image sets through deformable registration of the images acquired at some known phases. First, Active Demons registration algorithm was employed to estimate the motion field between inhale and exhale phases. Then, images at an intermediate phase were reconstructed by a linear interpolation of the deformation coefficients. The experiment results showed that the images at intermediate phases could be reconstructed efficiently. The quantitative analysis of landmark point displacements showed that 3 mm accuracy was achievable. The different maps of reconstructed and acquired images illustrated the similar level of success. The proposed method can accurately reconstruct images at intermediate phases of lung 4D-CT data.

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